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References
World Health Organization. WHO Traditional Medicine Strategy 2014–2023. [Last accessed on 2021 Mar 27]. http://apps.who.int/iris/bitstream/10665/92455/1/9789241506090eng.pdf.
Nebhinani M, Saini SK. Leveraging role of non-physician health workers in prevention and control of non-communicable diseases in India: Enablers and challenges. J Family Med Prim Care. 2021;10:595–600. – PMC – PubMed
Chung VCH, Wong CHL, Zhong CCW, Tjioe YY, Leung TH, Griffiths SM. Traditional and complementary medicine for promoting health ageing in WHO Western pacific region: Policy implications from utilization pattern and current evidence. Integr Med Res. 2021;10:100469. – PMC – PubMed
Nielsen A, Knoblauch NTM, Dobos GJ, Michalsen A, Kaptchuk TJ. The effect of Gua Sha treatment on the microcirculation of surface tissue: A pilot study in healthy subjects. Explore. 2007;3:456–66. – PubMed
Morgan L. Nitric oxide: A challenge to chiropractic. J Can Chiropr Assoc. 2000;44:40–8.
Kakish R. A strigil from Roman Jordan: Evidence for personal care: Case study. MAA. 2015;15:63–70.
Cheatham SW, Lee M, Cain M, Baker R. The efficacy of instrument assisted soft tissue mobilization: A systemic review. J Can Chiropr Assoc. 2016;60:200–11. – PMC – PubMed
Lauche R, Wübbeling K, Lüdtke R, Cramer H, Choi KE, Rampp T, et al. Randomized controlled pilot study: Pain intensity and pressure pain thresholds in patients with neck and low back pain before and after traditional East Asian “gua sha” therapy. Am J Chin Med. 2012;40:905–17. – PubMed
Mehta P, Dhapte V. Cupping therapy: A prudent remedy for a plethora of medical ailments. J Tradit Complement Med. 2015;5:127–34. – PMC – PubMed
Braun M, Schwickert M, Nielsen A, Brunnhuber S. Effectiveness of traditional Chinese “gua sha” therapy in patients with chronic neck pain: A randomized controlled trial. Pain Med. 2011;12:362–9. – PubMed
Chen T, Liu N, Liu J, Zhang X, Huang Z, Zang Y, et al. Gua Sha, a press-stroke treatment of the skin, boosts the immune response to intradermal vaccination. Peer J. 2016;4:e2451. – PMC – PubMed
Cao S, Zheng M, Hua Y, Chen G, Keep RF, Xi G. Hematoma changes during clot resolution after experimental intracerebral hemorrhage. Stroke. 2016;47:1626–31. – PMC – PubMed
Epperla N, Mazza JJ, Yale SH. A review of clinical signs related to ecchymosis. WMJ. 2015;114:61–5. – PubMed
Regino WO, Velasco H, Sandoval H. The protective role of bilirubin in human beings. Rev Col Gastroenterol. 2009;24:293–301.
Ryter SW, Choi AM. Heme oxygenase-1/carbon monoxide. Am J Respir Cell Mol Biol. 2009;41:251–60. – PMC – PubMed
Nitti M, Furfaro AL, Mann GE. Heme oxygenase dependent bilirubin generation in vascular cells: A role in preventing endothelial dysfunction in local tissue microenvironment? Front Physiol. 2020;11:23. – PMC – PubMed
Chen TM, Li J, Liu L, Fan L, Li XY, Wang YT, et al. Effects of heme oxygenase-1 upregulation on blood pressure and cardiac function in an animal model of hypertensive myocardial infarction. Int J Mol Sci. 2013;14:2684–706. – PMC – PubMed
Naito Y, Takagi T, Higashimura Y. Heme oxygenase-1 and anti-inflammatory M2 macrophages. Arch Biochem Biophys. 2014;564:83–8. – PubMed
Duvigneau J, Esterbauer H, Kozlov AV. Role of heme oxygenase as a modulator of heme-mediated pathway. Antioxidants (Basel) 2019;8:475. – PMC – PubMed
Jansen T, Daiber A. Direct antioxidant properties of bilirubin and biliverdin. Is there a role for biliverdin reductase? Front Pharmacol. 2012;3:30. – PMC – PubMed
Tsai MT, Tarng DC. Beyond a measure of liver function-Bilirubin acts as a potential cardiovascular protector in chronic kidney disease patients. Int J Mol Sci. 2019;20:117. – PMC – PubMed
Watchko JF. Kernicterus and the molecular mechanisms of bilirubin-induced CNS injury in newborns. Neuromolecular Med. 2006;8:513–29. – PubMed
Gozzelino R, Jeney V, Soares MP. Mechanisms of cell protection by heme oxygenase-1. Annu Rev Pharmacol Toxicol. 2010;50:323–54. – PubMed
Ogun AS, Adeyinka A. Biochemistry, transferrin. StatPearls. Treasure Island, FL: StatPearls Publishing; 2018.
Kim HP, Ryter SW, Choi AM. CO as a cellular signaling molecule. Annu Rev Pharmacol Toxicol. 2006;46:411–49. – PubMed
Sheikh SZ, Hegazi RA, Kobayashi T, Onyiah JC, Russo SM, MatsuoKa K, et al. An anti-inflammatory role for carbon monoxide and heme oxygenase-1 in chronic Th2-mediated murine colitis. J Immunol. 2011;186:5506–13. – PMC – PubMed
Morse D, Pischke SE, Zhou Z, Davis RJ, Flavell RA, Loop T, et al. Suppression of inflammatory cytokine production by carbon monoxide involves the JNK pathway and AP-1. J Biol Chem. 2003;278:36993–8. – PubMed
Sharma JN, Al-Omran A, Parvathy SS. Role of nitric oxide in inflammatory diseases. Inflammopharmacology. 2007;15:252–9. – PubMed
Cals-Grierson MM, Ormerod AD. Nitric oxide function in the skin. Nitric Oxide. 2004;10:179–93. – PubMed
Zhang JM, An J. Cytokines, inflammation, and pain. Int Anesthesiol Clin. 2007;45:27–37. – PMC – PubMed
Cao J, Inoue K, Li X, Drummond G, Abraham NG. Physiological significance of heme oxygenase in hypertension. Int J Biochem Cell Biol. 2008;41:1025–33. – PMC – PubMed
Paine A, Eiz-Vesper B, Blasczyk R, Immenschuh S. Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential. Biochem Pharmacol. 2010;80:1895–903. – PubMed
Yang M, Zhang H, Yue R, Shi Q, Bian Y. Gua Sha attenuates thermal hyperalgesia and decreases proinflammatory cytokine expression in serum in rats with lumbar disc herniation induced by autologous nucleus pulposus. J Trad Chin Med. 2018;38:698–704. – PubMed
Tsuda M. Microglia in the spinal cord and neuropathic pain. J Diabetes Investig. 2016;7:17–26. – PMC – PubMed
Wu HY, Tang XQ, Mao XF, Wang YX. Autocrine interleukin-10 mediates glucagon-like peptide-1 receptor-induced spinal microglial β-endorphin expression. J Neurosci. 2017;37:11701–14. – PMC – PubMed
Nascimento CGO, Branco LGS. Antinociception synergy between the peripheral and spinal sites of the heme oxygenase-carbon monoxide pathway. Braz J Med Biol Res. 2009;42:141–7. – PubMed
Kwong KK, Kloetzer L, Wong KK, Ren JQ, Kuo B, Jiang Y, et al. Bioluminescence imaging of heme oxygenase-1 upregulation in the Gua Sha procedure. J Vis Exp. 2009:1385. – PMC – PubMed
Kidd BL, Urban LA. Mechanisms of inflammatory pain. Br J Anaesth. 2001;87:3–11. – PubMed
Cunha FQ, Moncada S, Liew FY. Interleukin-10 (IL-10) inhibits the induction of nitric oxide synthase by interferon-γ in murine macrophages. Biochem Biophys Res Commun. 1992;182:1155–9. – PubMed
Hervera A, Leánez S, Negrete R, Motterlini R, Pol O. Carbon monoxide reduces neuropathic pain and spinal microglial activation by inhibiting nitric oxide synthesis in mice. PLoS One. 2012;7:e43693. – PMC – PubMed
Hamza M, Wang XM, Wu T, Brahim JS, Rowan JS, Dionne RA. Nitric oxide is negatively correlated to pain during acute inflammation. Mol Pain. 2010;6:55. – PMC – PubMed
Burke T. Nitric oxide series, part seven: Nitric oxide (NO) and relief of pain. 2009. [[Last accessed on 2020 Sep 15]]. Available from: http://www.diabetesincontrol.com/nitric-oxide-series-part-sevennitric-ox…
Cury Y, Picolo G, Gutierrez VP, Ferreira SH. Pain and analgesia: The dual effect of nitric oxide in the nociceptive system. Nitric Oxide. 2011;25:243–54. – PubMed
Ropero Peláez FJ, Taniguchi S. The gate theory of pain revisited: Modeling different pain conditions with a parsimonious neurocomputational model. Neural Plast 2016. 2016 4131395. – PMC –